Developmental cascades linking stress inoculation, arousal regulation, and resilience

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Developmental Cascades Linking Stress Inoculation, Arousal Regulation, and Resilience

Stressful experiences that are challenging but not overwhelming appear to promote the development of arousal regulation and resilience. Variously described in studies of humans as inoculating, steeling, or toughening, the notion that coping with early life stress enhances arousal regulation and resilience is further supported by longitudinal studies of squirrel monkey development. Exposure to e...

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Seeding Stress Resilience through Inoculation

Stress is a generalized set of physiological and psychological responses observed when an organism is placed under challenging circumstances. The stress response allows organisms to reattain the equilibrium in face of perturbations. Unfortunately, chronic and/or traumatic exposure to stress frequently overwhelms coping ability of an individual. This is manifested as symptoms affecting emotions ...

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Prefrontal plasticity and stress inoculation-induced resilience.

Coping with mild early life stress tends to make subsequent coping efforts more effective and therefore more likely to be used as a means of arousal regulation and resilience. Here we show that this developmental learning-like process of stress inoculation increases ventromedial prefrontal cortical volumes in peripubertal monkeys. Larger volumes do not reflect increased cortical thickness but i...

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Stress, vulnerability and resilience, a developmental approach

BACKGROUND The origins of mental disorders arise often in childhood. Early life is a period of unique sensitivity with long lasting effects on mental health. However, the mechanisms for these effects remain unclear. OBJECTIVE This thesis describes a variety of studies using a developmental framework to promote greater understanding of the influence of nature (genotypes) and nurture (e.g., env...

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Stress inoculation-induced indications of resilience in monkeys.

The negative consequences of stress are well-recognized in mental health research. Exposure to early life stressors, for example, increases the risk for the development of mood, anger, anxiety, and substance abuse disorders. Interestingly, however, early life stressors have also been linked to the subsequent development of resilience. Variously described as inoculating, immunizing, steeling, to...

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ژورنال

عنوان ژورنال: Frontiers in Behavioral Neuroscience

سال: 2009

ISSN: 1662-5153

DOI: 10.3389/neuro.08.032.2009